Joel Walker

Career

  • 2024 – Current Senior Lecturer, University of Vienna, Vienna, Austria, Department of Food Chemistry and Toxicology, Taught Masters students in seminar and practical courses in food chemistry and toxicology
  • 2023 – 2024 External Senior Lecturer, University of Vienna, Vienna, Austria, Department of Food Chemistry and Toxicology, Taught Masters students in seminar and practical courses in food chemistry and toxicology
  • 2022 – 2023 Part-time Lecturer, University of Vienna, Vienna, Austria, Department of Analytical Chemistry, Taught Bachelors students in the analytical chemistry practical course
  • 2022 Part-time Lecturer, University of Vienna, Vienna, Austria, Department of Food Chemistry and Toxicology, Taught Masters students in seminar and practical courses in food chemistry and toxicology
  • 2012 – 2015 Marie Curie Intra-European Fellow, University of Naples “Federico II”, Naples, Italy Department of Agricultural Sciences (Vitaglione group). Topic: Checking Melanoidins Satiating Efficiency Through Evaluation of Human Gut-Brain Response to Novel-Bread Ingestion (CHECKMATE-TO-HUNGER).
  • 2009 – 2012 Postdoctoral Fellow, University of Vienna, Vienna, Austria, Department of Nutritional and Physiological Chemistry (V. Somoza group), Topic: Bioactive plant compounds in vitro and in vivo
  • 2005 – 2009 Postdoctoral Fellow, University of Wisconsin – Madison, Madison, Wisconsin, USA Department of Nutritional Sciences (Eide group), Topic: Human zinc-transporter zip13 cellular localization by immunofluorescence microscopy
  • 1998 – 2005 PhD Trainee, Oregon Health & Science University, Portland, Oregon, USA,Department of Biochemistry and Molecular Biology (Lutsenko group),Topic: Molecular mechanisms of copper transfer in human cells

Education

  • 1998 – 2005 PhD in Biochemistry and Molecular Biology, Oregon Health & Science University, Portland, Oregon, USA, Member of the Lutsenko group. Thesis title: “Molecular mechanisms of copper transfer from the metallochaperone Atox1 to the Wilson Disease Protein”
  • 1994 – 1998 BSc in Biochemistry (cum laude), University of Dayton, Dayton, Ohio, USA

Publications

  • Walker JM, Mennella I, Ferracane R, Tagliamonte S, Holik AK, Hölz K, Somoza MM, Somoza V, Fogliano V, Vitaglione P. “Melanoidins from coffee and bread differentially influence energy intake: A randomized controlled trial of food intake and gut-brain response.” Journal of Functional Foods (2020), DOI: 10.1016/j.jff.2020.104063.
  • Walker J, Imboeck JM, Walker JM, Maitra A, Haririan H, Rausch-Fan X, Dodds M, Inui T, Somoza V. “Magnolia officinalis L. fortified gum improves resistance of oral epithelial cells against inflammation.” American Journal of Chinese Medicine (2016), 44(6): 1167-1185.
  • Walker J, Hosiner A, Kergoat S, Walker JM, Somoza V. “Chewing unflavored gum does not reduce cortisol levels during a cognitive task but increases the response of the sympathetic nervous system.” Physiology & Behavior (2016), 154:8-14.
  • Soares DJ, Walker J, Pignitter M, Walker JM, Imboeck JM, Ehrnhoefer-Ressler MM, Montenegro Brasil I, Somoza V. “Pitanga (Eugenia uniflora L.) fruit juice and two major constituents thereof exhibit anti-inflammatory properties in human gingival and oral gum epithelial cells.” Food & Function (2014), 5: 2981-2988.
  • Walker JM, Maitra A, Walker J, Ehrnhoefer-Ressler MM, Inui T, Somoza V. “Identification of Magnolia officinalis L. bark extract as the most potent anti-inflammatory of four plant extracts.” American Journal of Chinese Medicine (2013), 41(3): 531-44.
  • Ehrnhoefer-Ressler MM, Fricke K, Pignitter M, Walker JM, Walker J, Rychlik M, Somoza V. “Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts.” Journal of Agricultural and Food Chemistry (2013), 61(14): 3451-9.
  • Jeong J*, Walker JM*, Wang F, Park JG, Palmer AE, Giunta C, Rohrbach M, Steinmann B, Eide DJ. “Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome.” Proceedings of the National Academy of Sciences of the United States of America (2012), 109(51): E3530-8.
  • Andersen G, Burkon A, Sulzmaier FJ, Walker JM, Leckband G, Fuhst R, Erbersdobler HF, Somoza V. “High dose of dietary resveratrol enhances insulin sensitivity in healthy rats but does not lead to metabolite concentrations effective for SIRT1 expression.” Molecular Nutrition & Food Research (2011), 55(8): 1197-1206.
  • LeShane ES, Shinde U, Walker JM, Barry AN, Blackburn NJ, Ralle M, Lutsenko S. “Interactions between copper-binding sites determine the redox status and conformation of the regulatory N-terminal domain of ATP7B.” Journal of Biological Chemistry (2010), 285(9): 6327-6336.
  • Walker JM, Huster D, Ralle M, Morgan CT, Blackburn NJ, Lutsenko S. “The N-terminal metal-binding site 2 of the Wilson’s Disease protein plays a key role in the transfer of copper to Atox1.” Journal of Biological Chemistry (2004), 279(15): 15376-15384.
  • Lutsenko S, Tsivkovskii R, Walker JM. “Functional properties of the human copper-transporting ATPase ATP7B (the Wilson’s Disease protein) and regulation by metallochaperone Atox1.” Annuls of the New York Academy of Sciences (2003), 986: 204-211.
  • Lutsenko S, Efremov RG, Tsivkovskii R, Walker JM. “Human copper-transporting ATPase ATP7B (the Wilson's Disease protein): biochemical properties and regulation.” Journal of Bioenergetics and Biomembranes (2002), 34(5): 351-362.
  • Walker JM, Tsivkovskii R, Lutsenko S. “Metallochaperone Atox1 transfers copper to the N-terminal domain of the Wilson’s Disease protein and regulates its catalytic activity” Journal of Biological Chemistry (2002), 277(31): 27953-27959.

Awards

  • 2012 Marie Curie Intra-European Fellow Award (n° 300815)
  • 2008 Individual Ruth L. Kirschstein National Research Service Award Fellowship (F32 GM079995-01A1)
  • 2007 National Research Service Training Award Fellowship, University of Wisconsin – Madison
  • 2001 National Research Service Training Award Fellowship, Oregon Health & Science University
  • 2000 Tartar Research Fellowship, Medical Research Foundation, Oregon
  • 1997 Biochemistry Research Fellowship, University of Dayton
  • 1994 – 1998 Dean of Arts and Sciences Scholarship, University of Dayton

Oral Presentations

  • Walker JM, Mennella I, Somoza V, Fogliano V, Vitaglione P. “Coffee melanoidins-enriched bread but not bread crust-enriched bread increases satiety and improves glucose metabolism in the short term.” Third International Congress on Cocoa, Coffee and Tea, (2015), Aveiro, Portugal.
  • Walker JM, Wang F, Eide DJ. “The human zinc transporter Zip13 mobilizes zinc from a vesicular compartment.” 2008 Gordon Graduate Research Seminar on Bioinorganic Chemistry, (2008), Ventura, California, USA.
  • Walker JM, Lutsenko S. “Copper transfer from the copper chaperone Atox1 to the Wilson’s disease protein.” The 19th Annual OHSU Student Research Forum (2001). Portland, Oregon, USA.

Poster Presentations

  • Walker JM, Mennella I, Somoza V, Fogliano V, Vitaglione P. Checking melanoidins satiating efficiency through evaluation of human gut-brain response to novel-bread ingestion (CHECKMATE-TO-HUNGER). Second International Conference on Cocoa, Coffee and Tea, (2013), Naples, Italy.
  • Walker JM, Wang F, Eide DJ. The human zinc transporter Zip13 mobilizes zinc from a vesicular compartment. 2008 Gordon Graduate Research Seminar on Bioinorganic Chemistry, (2008), Ventura, California, USA.
  • Walker JM, Wang F, Eide DJ. The human zinc transporter Zip13. FASEB Summer Research Conference on Trace Element Micronutrients: Integrating Basic and Applied Research, (2006), Snowmass, Colorado, USA.
  • Walker JM, Tsivkovskii R, Huster D, Ralle M, Morgan C, Blackburn N, Lutsenko S. The N-terminal metal-binding site 2 of the Wilson’s Disease protein plays a key role in the transfer of copper from Atox1. 4th International Meeting on “Copper Homeostasis and Its Disorders: Molecular and Cellular Aspects,” (2004), Ischia, Italy.
  • Walker JM, Tsivkovskii R, Lutsenko S. Metallochaperone Atox1 transfers copper to the N-terminal domain of the Wilson’s Disease protein and regulates its catalytic activity. Copper Homeostasis and Its Disorders: Molecular and Cellular Aspects, (2002), Ischia, Italy.
  • Walker JM and Lutsenko S. Copper transfer from the human copper chaperone HAH1 to the Wilson’s Disease protein. Society for Experimental Biology, (2001), Canterbury, England.
  • Singer SS, Codispoti C, Glatz S, Karnak D, Lopper M, Sonnefeld C, Walker J. Rat cytosol liver fatty-acid-binding protein (LFABP) and intestinal FABP (IFABP) levels and ratios of these FABP levels vary with age and gender, in hypertension, and after clofibrate. Federation of American Societies for Experimental Biology, (1998), San Francisco, CA, USA.